The Thule Bed Rider is the simplest bike carrying solution for your pickup. The Bed Rider's crossbar spans your bed using an expanding cam mechanism and sticky rubber feet to hold itself in place. Installation and removal are both equally easy. The Bed Rider holds two bikes, and in really wide beds extra BR1 mounts can be added. For security you can attach basic cable locks through the heavy-duty metal loops.
Bottom Line: A no-drill, no problem truck bed bike rack.